. Tetraphilin--A 4-helix proton channel crafted with a tetraphenylporphyrin framework. J Am
Secondary framework and assembly system of an oligomeric channel protein. Biochemistry. 1985; 24:1915?920. [PubMed: 4016091] 70. Music LZ, Hobaugh MR, Shustak C, Cheley S, Bayley H, Gouaux JE. Structure of staphylococcal alpha-hemolysin, a heptameric transmembrane pore. Science. 1996; 274:1859?866. [PubMed: 8943190] seventy one. Howorka S, Cheley S, Bayley H. Sequence-specific detection of PF-04447943 References PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/24021036 individual DNA strands employing engineered nanopores. Nat Biotechnol. 2001; 19:636?39. [PubMed: 11433274] 72. Tsitrin Y, Morton CJ, El Bez C, Paumard P, Velluz MC, Adrian M, Dubochet J, Parker MW, Lanzavecchia S, van der Goot FG. Conversion of a transmembrane to a watersoluble protein sophisticated by an individual issue mutation. Nat Struct Biol. 2002; 9:729?33. [PubMed: 12219082] seventy three. Nablo BJ, Halverson KM, Robertson JWF, Nguyen TL, Panchal RG, Gussio R, Bavari S, Krasilnikov OV, Kasianowicz JJ. Sizing the Bacillus anthracis PA(sixty three) channel with nonelectrolyte poly(ethylene glycols). Biophys J. 2008; ninety five:1157?164. [PubMed: 18645196] 74. Urry DW. Gramicidin-A transmembrane channel--proposed PI (L,D) helix. Proc Natl Acad Sci U S A. 1971; 68:672?76. [PubMed: 5276779] seventy five. CK-2017357 supplier Stankovic CJ, Wnt-C59 Epigenetics Heinemann SH, Delfino JM, Sigworth FJ, Schreiber SL. Transmembrane channels centered on tartaric acid gramicidin-A hybrids. Science. 1989; 244:813?seventeen. PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/25738799 [PubMed: 2471263] 76? Hladky SB, Haydon DA. Discreteness of conductance change in bimolecular lipid AS-3201 In Vitro membranes in existence of sure antibiotics. Nature. 1970; 225:451?fifty three. First single-molecule experiment which has a biomolecule, below gramicidin. [PubMed: 5411119]Curr Opin Biotechnol. Writer manuscript; offered in PMC 2011 June 23.NIH-PA Writer Manuscript NIH-PA Writer Manuscript NIH-PA Writer ManuscriptMajd et al.Page77. Fox RO, Richards FM. A voltage-gated ion channel model inferred in the crystal construction of alamethicin at one.5-?resolution. Nature. 1982; 300:325?30. [PubMed: 6292726] seventy eight. Li C, Salditt T. Framework of magainin and alamethicin in design membranes examined by X-ray reflectivity. Biophys J. 2006; 91:3285?300. [PubMed: 16920839] seventy nine. Vogel H. Comparison in the conformation and orientation of alamethicin and melittin in lipidmembranes. Biochemistry. 1987; 26:4562?572. [PubMed: 3663608] 80. Pott T, Paternostre M, Dufourc EJ. A comparative analyze in the action of melittin on sphingomyelin and phosphatidylcholine bilayers. Eur Biophys J Biophys. 1998; 27:237?forty five. eighty one. Chen M, Khalid S, Sansom MSP, Bayley H. Outer membrane protein G. engineering a peaceful pore for biosensing. Proc Natl Acad Sci U S A. 2008; a hundred and five:6272?277. [PubMed: 18443290] 82. Tamm LK, McConnell HM. Supported phospholipid-bilayers. Biophys J. 1985; 47:a hundred and five?13. [PubMed: 3978184] 83. Majd S, Mayer M. Hydrogel stamping of arrays of supported lipid bilayers with a variety of lipid compositions for your screening of drug-membrane and protein-membrane interactions.. Tetraphilin--A 4-helix proton channel constructed with a tetraphenylporphyrin framework. J Am Chem Soc. 1992; 114:9656?9657. 67. Akerfeldt KS, Lear JD, Wasserman ZR, Chung LA, Degrado WF. Synthetic peptides as designs for ion channel proteins.